A multidisciplinary team approach to a neonate with a rare primary mediastinal tumor: a case report

Primary mediastinal tumors in children are extremely rare, consisting of under 0.1% of neoplasms in this age group. Of these, teratomas represent 8%–16% of the cases. Clinical presentation depends primarily on the tumor’s size, location, malignancy, and growth rate. Large tumor masses may compress structures in the thorax and cause respiratory distress syndrome, superior vena cava syndrome, or cardiac tamponade. This report describes a neonate with respiratory distress and heart failure shortly after birth due to a large mediastinal tumor mass. The child underwent successful surgery and has no signs of relapse during the 2-year follow-up. A complex approach and a multidisciplinary team are the cornerstone in the treatment of neonates with mediastinal tumors. Complete tumor resection is the gold standard treatment.

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Publication Details

Journal
Folia Medica
Published
2026-06-17
DOI
https://doi.org/10.3897/folmed.68.e173882
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00
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article

A multidisciplinary team approach to a neonate with a rare primary mediastinal tumor: a case report

Dimitar Pechilkov, Радка Масларска, Anna Kaneva-Nencheva, Stefka Stoichkova et al.
Folia Medica
Myasthenia Gravis and Thymoma
article

A multidisciplinary team approach to a neonate with a rare primary mediastinal tumor: a case report

Dimitar Pechilkov, Радка Масларска, Anna Kaneva-Nencheva, Stefka Stoichkova, Hristo Shivachev
article en

Abstract

Primary mediastinal tumors in children are extremely rare, consisting of under 0.1% of neoplasms in this age group. Of these, teratomas represent 8%–16% of the cases. Clinical presentation depends primarily on the tumor’s size, location, malignancy, and growth rate. Large tumor masses may compress structures in the thorax and cause respiratory distress syndrome, superior vena cava syndrome, or cardiac tamponade. This report describes a neonate with respiratory distress and heart failure shortly after birth due to a large mediastinal tumor mass. The child underwent successful surgery and has no signs of relapse during the 2-year follow-up. A complex approach and a multidisciplinary team are the cornerstone in the treatment of neonates with mediastinal tumors. Complete tumor resection is the gold standard treatment.

Folia MedicaVol. 68(3)
Tokuda Hospital (BG), National Institute of Emergency Medicine "Pirogov" (BG), National Heart Hospital (BG)
Good health and well-being
Openalex Percentile: Top 7%
Myasthenia Gravis and Thymoma
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