Successful Treatment of Granuloma Faciale With Deep Dermal Inflammatory Infiltration Using Intralesional Corticosteroid Injections: A Case Report

A 46-year-old man presented with asymptomatic dark reddish nodules on the left nasal ala and lower jaw, including a 1-cm nodule on the nasal ala. Histopathological examination revealed diverse inflammatory cell infiltration extending into the deep dermis and the presence of a grenz zone. Based on these findings, he was diagnosed with granuloma faciale (GF). Intralesional corticosteroid injections were selected because of their strong anti-inflammatory effects and efficacy in treating deep dermal lesions. Although various treatment modalities have been attempted, GF is often refractory to treatment. In this case, the lesion resolved completely after three intralesional corticosteroid injections.

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Publication Details

Journal
Cureus
Published
2026-06-17
DOI
https://doi.org/10.7759/cureus.111010
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Successful Treatment of Granuloma Faciale With Deep Dermal Inflammatory Infiltration Using Intralesional Corticosteroid Injections: A Case Report

Shota Uchida, Riichiro Abe, Tatsuya Katsumi, Mioka Homma et al.
Cureus
Autoimmune and Inflammatory Disorders
article

Successful Treatment of Granuloma Faciale With Deep Dermal Inflammatory Infiltration Using Intralesional Corticosteroid Injections: A Case Report

Shota Uchida, Riichiro Abe, Tatsuya Katsumi, Mioka Homma, Ryoya Ohashi
article en

Abstract

A 46-year-old man presented with asymptomatic dark reddish nodules on the left nasal ala and lower jaw, including a 1-cm nodule on the nasal ala. Histopathological examination revealed diverse inflammatory cell infiltration extending into the deep dermis and the presence of a grenz zone. Based on these findings, he was diagnosed with granuloma faciale (GF). Intralesional corticosteroid injections were selected because of their strong anti-inflammatory effects and efficacy in treating deep dermal lesions. Although various treatment modalities have been attempted, GF is often refractory to treatment. In this case, the lesion resolved completely after three intralesional corticosteroid injections.

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Autoimmune and Inflammatory Disorders
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