Highlights of 2025: Advances in the T‐Cell Regulation of Germinal Center Response

ABSTRACT In this 2025 Highlight, we summarize recent advances in T‐cell regulation of germinal center (GC) responses. These studies reveal new mechanisms governing follicular helper T (T FH )‐cell function and their control of GC dynamics and B‐cell fate decisions, providing insights for rational vaccine design and the prevention of GC dysregulation.

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Publication Details

Journal
Immunology and Cell Biology
Published
2026-06-16
DOI
https://doi.org/10.1111/imcb.70141
Primary Topic
T-cell and B-cell Immunology
Type
article
Field-Weighted Citation Impact
0.00
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article

Highlights of 2025: Advances in the T‐Cell Regulation of Germinal Center Response

Xinting Zhou, Zhian Chen
Immunology and Cell Biology
T-cell and B-cell Immunology
article

Highlights of 2025: Advances in the T‐Cell Regulation of Germinal Center Response

Xinting Zhou, Zhian Chen
article en

Abstract

ABSTRACT In this 2025 Highlight, we summarize recent advances in T‐cell regulation of germinal center (GC) responses. These studies reveal new mechanisms governing follicular helper T (T FH )‐cell function and their control of GC dynamics and B‐cell fate decisions, providing insights for rational vaccine design and the prevention of GC dysregulation.

Immunology and Cell Biology
The University of Queensland (AU)
Openalex Percentile: Top 10%
T-cell and B-cell Immunology
DOISourceOpenAlex
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