Recalibration and Validation of a Risk Scoring Tool to predict Multi-Drug Resistant <i>Pseudomonas aeruginosa</i>
Abstract We recalibrated a risk score to identify difficult-to-treat resistant Pseudomonas aeruginosa among 197 ICU patients with bloodstream or respiratory infection. Prevalence was 6%. Models showed moderate discrimination (c-statistics 0.71–0.74), low sensitivity (18%), and high specificity (94%–96%), highlighting the need for local validation and consideration of performance tradeoffs.
Authors
- Emily L. Heil (ORCID: https://orcid.org/0000-0002-6644-6684)
- Kimberly C. Claeys (ORCID: https://orcid.org/0000-0001-6895-604X)
- Megan Dunning
- Hyunuk Seung (ORCID: https://orcid.org/0000-0002-4219-8874)
- Nhu Le (ORCID: https://orcid.org/0009-0003-2964-044X)
Institutions
- University of Maryland, Baltimore (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2026-06-16
- DOI
- https://doi.org/10.1093/ofid/ofag359
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00