Synthesis and Characterization of a Lumacaftor-related Impurity: Aminomethyl Pyridinebenzoic Acid (AMPBA)

Lumacaftor (1, Figure 1) is a benzodioxole derivative used in combination with Ivacaftor in the treatment of cystic fibrosis in patients age 12 years and older.1-7 Lumacaftor is marketed under the ...

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Publication Details

Journal
Organic Preparations and Procedures International
Published
2026-06-17
DOI
https://doi.org/10.1080/00304948.2026.2672751
Primary Topic
Cystic Fibrosis Research Advances
Type
article
Field-Weighted Citation Impact
0.00
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article

Synthesis and Characterization of a Lumacaftor-related Impurity: Aminomethyl Pyridinebenzoic Acid (AMPBA)

M. Padma, Srinu Karnati, Abhishek Shankar Saxena, Hanmanth Rao L
Organic Preparations and Procedures International
Cystic Fibrosis Research Advances
article

Synthesis and Characterization of a Lumacaftor-related Impurity: Aminomethyl Pyridinebenzoic Acid (AMPBA)

M. Padma, Srinu Karnati, Abhishek Shankar Saxena, Hanmanth Rao L
article en

Abstract

Lumacaftor (1, Figure 1) is a benzodioxole derivative used in combination with Ivacaftor in the treatment of cystic fibrosis in patients age 12 years and older.1-7 Lumacaftor is marketed under the ...

Organic Preparations and Procedures International
Andhra University (IN), Sugen Life Sciences (India) (IN)
Openalex Percentile: Top 8%
Cystic Fibrosis Research Advances
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