Comparative Imaging of Allergic Fungal Sinusitis With Orbital and Intracranial Extension: A Case Report

Allergic fungal sinusitis (AFS) is classified as a non-invasive, immunologically mediated chronic rhinosinusitis. It can rarely mimic aggressive infectious or neoplastic disease. We present two companion cases demonstrating orbital apex compression without intracranial involvement and another case with epidural extension, respectively. These cases challenge the conventional understanding of AFS and emphasize the importance of advanced imaging. We propose a novel AFS aggression spectrum (AAS) to stratify disease severity and categorize the progressive imaging features of allergic fungal sinus disease within a four-tier diagnostic framework.

Authors

Publication Details

Journal
Cureus
Published
2026-06-17
DOI
https://doi.org/10.7759/cureus.111057
Primary Topic
Sinusitis and nasal conditions
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Comparative Imaging of Allergic Fungal Sinusitis With Orbital and Intracranial Extension: A Case Report

Gregory Wrubel, Jennifer Adams, Mehmet Albayram
Cureus
Sinusitis and nasal conditions
article

Comparative Imaging of Allergic Fungal Sinusitis With Orbital and Intracranial Extension: A Case Report

Gregory Wrubel, Jennifer Adams, Mehmet Albayram
article en

Abstract

Allergic fungal sinusitis (AFS) is classified as a non-invasive, immunologically mediated chronic rhinosinusitis. It can rarely mimic aggressive infectious or neoplastic disease. We present two companion cases demonstrating orbital apex compression without intracranial involvement and another case with epidural extension, respectively. These cases challenge the conventional understanding of AFS and emphasize the importance of advanced imaging. We propose a novel AFS aggression spectrum (AAS) to stratify disease severity and categorize the progressive imaging features of allergic fungal sinus disease within a four-tier diagnostic framework.

Cureus
Good health and well-being
Openalex Percentile: Top 7%
Sinusitis and nasal conditions
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.