SPECTRUM: Week 24 data for aflibercept 8 mg indicate improvements in patients with treatment-naïve nAMD and stable outcomes in patients with previously treated nAMD

Purpose: To present Week (W) 24 results from the SPECTRUM study on the real-world effectiveness and safety of aflibercept 8 mg in patients with treatment-naïve (TN) and previously treated (PT) neovascular age-related macular degeneration (nAMD). Methods: SPECTRUM (NCT06075147) is an ongoing, [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2026-06-17
DOI
https://doi.org/10.3205/26doc132
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

SPECTRUM: Week 24 data for aflibercept 8 mg indicate improvements in patients with treatment-naïve nAMD and stable outcomes in patients with previously treated nAMD

Aude Ambresin, Tobias Machewitz, Paolo Lanzetta, Hassiba Oubraham et al.
German Medical Science (German Research Foundation)
Retinal Diseases and Treatments
article

SPECTRUM: Week 24 data for aflibercept 8 mg indicate improvements in patients with treatment-naïve nAMD and stable outcomes in patients with previously treated nAMD

Aude Ambresin, Tobias Machewitz, Paolo Lanzetta, Hassiba Oubraham, Sarah Schlief, Susanne Oesch, C. Lange, Marion Munk, Peter Morgan-Warren, Andreas Stahl, Vasileios Konidaris, Clare Bailey, Varun Chaudhary, Martin Kirchner
article en

Abstract

Purpose: To present Week (W) 24 results from the SPECTRUM study on the real-world effectiveness and safety of aflibercept 8 mg in patients with treatment-naïve (TN) and previously treated (PT) neovascular age-related macular degeneration (nAMD). Methods: SPECTRUM (NCT06075147) is an ongoing, [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
CGIAR (FR), University of Udine (IT), University of Freiburg (DE), Universitätsmedizin Greifswald (DE), University Hospitals Bristol NHS Foundation Trust (GB), University Hospitals of Leicester NHS Trust (GB), Addiction Switzerland (CH), Bayer (Switzerland) (CH), Orthopädische Praxis (DE), Bayer (Germany) (DE), McMaster University (CA)
Openalex Percentile: Top 6%
Retinal Diseases and Treatments
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SPECTRUM: Week 24 data for aflibercept 8 mg indicate improvements in patients with treatment-naïve nAMD and stable outcomes in patients with previously treated nAMD — Aude Ambresin, Tobias Machewitz, et al. · German Medical Science (German Research Foundation) (2026) | TGRS Research Map | TGRS