Ligilactobacillus murinus modulates gut microbiota-derived 5-hydroxyindole to inhibit pseudorabies virus infection via activation of the aryl hydrocarbon receptor

mice. Collectively, these findings highlight that STING inhibits PRV infection by regulating L. murinus and 5-HI, which leads to activation of AhR.

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Publication Details

Journal
npj Biofilms and Microbiomes
Published
2026-06-17
DOI
https://doi.org/10.1038/s41522-026-01025-4
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00

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article

Ligilactobacillus murinus modulates gut microbiota-derived 5-hydroxyindole to inhibit pseudorabies virus infection via activation of the aryl hydrocarbon receptor

Jun-Hong Xing, Man-Jie Hu, Ying-Shi Yang, Yanlong Jiang et al.
npj Biofilms and Microbiomes
Gut microbiota and health
article

Ligilactobacillus murinus modulates gut microbiota-derived 5-hydroxyindole to inhibit pseudorabies virus infection via activation of the aryl hydrocarbon receptor

Jun-Hong Xing, Man-Jie Hu, Ying-Shi Yang, Yanlong Jiang, Yong-Lei Yang, Xin Cao, Guilian Yang, Wentao Yang, Nan Wang, Jianzhong Wang, Rongrong Zhang, Y. H. Yang, Lin-jiao Yu, M. Azeem Riaz, Bing Liu, Jing-Yi Pang, Ying Zhao, Hai-Bin Huang, Tian-Kui Guo, Yan Zeng, Chun-Feng Wang, Chun-Wei Shi
article en

Abstract

mice. Collectively, these findings highlight that STING inhibits PRV infection by regulating L. murinus and 5-HI, which leads to activation of AhR.

npj Biofilms and Microbiomes
Jilin University (CN), Jilin Agricultural University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 12%
Gut microbiota and health
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