Improving bedside airway tests accuracy for predicting difficult laryngoscopy using ultrasound-measured skin-to-epiglottis distance
BACKGROUND: This study aimed to assess the accuracy of a composite score combining ultrasound-measured skin-to-epiglottis distance (DSE), Upper Lip Bite Test (ULBT), and Modified Mallampati Test (MMT) in predicting difficult airway. METHODS: In this prospective observational study, 250 adults scheduled for elective surgery were assessed preoperatively using ULBT, MMT, and ultrasound measurement of DSE. A composite airway score was calculated by assigning one point for each of the following: DSE > 2.0 cm, ULBT class > I, and MMT grade > II. Difficult laryngoscopy was defined as Cormack-Lehane grade > 2, and difficult intubation as an Intubation Difficulty Scale > 5. The outcomes were the ability of the score and individual tests to predict difficult airway using area under the receiver operating characteristic curve (AUC). RESULTS: The incidence of difficult laryngoscopy and intubation was 12.8% and 6.8%, respectively. The composite score showed superior predictive accuracy compared to individual tests, with AUCs (95% confidence interval) of 0.77 (0.72-0.82) for difficult laryngoscopy and 0.83 (0.78-0.88) for difficult intubation. A score > 1 had negative predictive values of 93% for difficult laryngoscopy and 97% for difficult intubation. When all three tests were negative, the composite score had a sensitivity and negative predictive value of 100% for predicting difficult intubation. CONCLUSION: A composite airway score combining DSE, ULBT, and MMT can accurately predict difficult laryngoscopy and intubation. When all three parameters are negative, difficult intubation is very unlikely. Additionally, a score of < 2 rules out difficult laryngoscopy and intubation with 93% and 97% accuracy, respectively.
Authors
- Sherif Alaa Embaby
- Sherin Refaat (ORCID: https://orcid.org/0000-0003-3440-9333)
- Mostafa Nagy (ORCID: https://orcid.org/0000-0002-0560-962X)
- Mohamed Mansour (ORCID: https://orcid.org/0000-0001-8222-2165)
- Esraa Gamal Hamad
- Maha Mostafa
- Ahmed Hasanin
- Haytham Eltrabily
Institutions
- Cairo University (EG)
Publication Details
- Journal
- Journal of Anesthesia Analgesia and Critical Care
- Published
- 2026-06-17
- DOI
- https://doi.org/10.1186/s44158-026-00426-3
- Primary Topic
- Airway Management and Intubation Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cairo University
- Science and Technology Development Fund