Hepatocellular carcinoma muscle and skin metastasis: A case-report
A 55-year-old patient with chronic hepatitis B infection who developed hepatocellular carcinoma. The tumor was managed with primary therapeutic resection. On postoperative follow-up imaging, rising alpha-fetoprotein noted which led into contrast-enhanced MRI of abdomen. On Imaging review, an abdominal wall lesion suspected, which was more conspicuous on the post contrast images. There are several differential diagnosis for these soft tissue lesions which demonstrate many shared imaging characteristics. Musculoskeletal and cutaneous metastases from hepatocellular carcinoma are uncommon, though clinically critical since it changes management. We strongly recommend detailed evaluation of skin and musculoskeletal regions among these patients.
Authors
- Ali Nosrati Andevari (ORCID: https://orcid.org/0000-0002-8699-4688)
- Mahyar Daskareh (ORCID: https://orcid.org/0000-0001-5601-6392)
- Reihaneh Mortazavi Ardestani (ORCID: https://orcid.org/0000-0002-7601-9600)
- Fatemeh Abbası (ORCID: https://orcid.org/0009-0005-3321-5061)
Institutions
- Kerman University of Medical Sciences (IR)
- Hospital of the University of Pennsylvania (US)
- Islamic Azad University Tonekabon (IR)
- Shahid Beheshti University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Radiology Case Reports
- Published
- 2026-06-17
- DOI
- https://doi.org/10.1016/j.radcr.2026.05.067
- Primary Topic
- Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00