Rule-breaking in chemical synthesis

Challenging century-old rules of structure, bonding, and reactivity enables the discovery of new synthetic chemistry involving amides and anti-Bredt olefins.

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Publication Details

Journal
Science Advances
Published
2026-06-17
DOI
https://doi.org/10.1126/sciadv.aeg7124
Primary Topic
Advanced Synthetic Organic Chemistry
Type
article
Field-Weighted Citation Impact
0.00

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article

Rule-breaking in chemical synthesis

Kendall N. Houk, Jordan A. M. Gonzalez, Neil K. Garg, Giulianna A. Miseo
Science Advances
Advanced Synthetic Organic Chemistry
article

Rule-breaking in chemical synthesis

Kendall N. Houk, Jordan A. M. Gonzalez, Neil K. Garg, Giulianna A. Miseo
article en

Abstract

Challenging century-old rules of structure, bonding, and reactivity enables the discovery of new synthetic chemistry involving amides and anti-Bredt olefins.

Science AdvancesVol. 12(25)
University of California, Los Angeles (US)
National Science Foundation, National Institute of General Medical Sciences
Openalex Percentile: Top 13%
Advanced Synthetic Organic Chemistry
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