Ecthyma Gangrenosum Caused by Streptococcus pyogenes: A Case Report

Ecthyma gangrenosum (EG) is an uncommon infectious vasculitis presenting as erythematous macules that develop into characteristic black eschars most commonly in the setting of bacteremia. While EG is most often associated with Pseudomonas aeruginosa infection, we present a case of EG-like skin lesions caused by Streptococcus pyogenes, an atypical causative organism, in an immunocompromised individual. Resolution was achieved following treatment with disease-specific intravenous antibiotics, adjuvant topical therapies, and stabilization of other underlying medical conditions that precipitated the infection.

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Publication Details

Journal
Cureus
Published
2026-06-17
DOI
https://doi.org/10.7759/cureus.111039
Primary Topic
Infections and bacterial resistance
Type
article
Field-Weighted Citation Impact
0.00

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article

Ecthyma Gangrenosum Caused by Streptococcus pyogenes: A Case Report

J. Connor Holman, Kiley Brady Kirby, Moses H Cheng
Cureus
Infections and bacterial resistance
article

Ecthyma Gangrenosum Caused by Streptococcus pyogenes: A Case Report

J. Connor Holman, Kiley Brady Kirby, Moses H Cheng
article en

Abstract

Ecthyma gangrenosum (EG) is an uncommon infectious vasculitis presenting as erythematous macules that develop into characteristic black eschars most commonly in the setting of bacteremia. While EG is most often associated with Pseudomonas aeruginosa infection, we present a case of EG-like skin lesions caused by Streptococcus pyogenes, an atypical causative organism, in an immunocompromised individual. Resolution was achieved following treatment with disease-specific intravenous antibiotics, adjuvant topical therapies, and stabilization of other underlying medical conditions that precipitated the infection.

Cureus
U.S. Navy, Defense Health Agency
Good health and well-being
Openalex Percentile: Top 8%
Infections and bacterial resistance
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