Uncommon Tumor, Unusual Site, and Unconventional Behavior: Report of a Gastric Composite Gangliocytoma/Neuroma and Neuroendocrine Tumor (CoGNET) With Metastases
came an important distinction between epithelial and non-epithelial neoplasms, and the possibility of composite tumor in certain organs, including the duodenum, the spine and the middle ear. In particular, the formerly termed gangliocytic paraganglioma of the duodenum has been renamed as "composite gangliocytoma/neuroma and neuroendocrine tumor (CoGNET)." We present an unusual CoGNET arising in the stomach, displaying distinctive histomorphologies in primary tumor and metastases. Additionally, we discuss diagnostic pitfalls and highlight the importance of recognizing the combined features that can be seen in this rare, potentially malignant, entity.
Authors
- Pooja Navale (ORCID: https://orcid.org/0000-0002-6693-1989)
- Nikolaos Trikalinos
- Alicia Dessain
- Vikas Prasad
Institutions
- Washington University in St. Louis (US)
- University of Missouri Hospital (US)
- Cooper University Health Care (US)
Publication Details
- Journal
- International Journal of Surgical Pathology
- Published
- 2026-06-16
- DOI
- https://doi.org/10.1177/10668969261457873
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 0.00