Prostate Cancer – 20-Year Comparative Mortality and Survival Analysis by Age, Race/Ethnicity, Stage, Grade, Disease Duration and Cohort Entry Period: A Systematic Review of 648,114 cases for Diagnosis Years 1975-2022

Prostate cancer is a major cause of disease and mortality among older men (mean age 67.3 years old) in the United States and globally. Given the biological heterogeneity of this cancer in this short- and long-term United States retrospective population-based analysis, the focus is on incidence, mortality, and survival by age, race/ethnicity, stage, and severity in cohort entry time periods (1975-99 and 2000-22), and disease duration. This comparative cohort short- and long-term study is intended to provide age-adjusted epidemiologic and demographic survival and mortality data for convenient reference by all physicians, scientists, insurance underwriters, and others interested in cancer mortality follow-up.