Mild Thrombocytopenia at Admission to Labor and Delivery: Implications for Postpartum Hemorrhage

BACKGROUND: Postpartum hemorrhage remains a leading cause of severe maternal morbidity and mortality. The association between mild thrombocytopenia and postpartum blood loss or red blood cell transfusion has not been well studied. OBJECTIVE: To evaluate whether mild thrombocytopenia at admission to labor and delivery is associated with increased rates of postpartum hemorrhage and packed red blood cell transfusion. STUDY DESIGN: or Mann-Whitney U test. A multivariable logistic regression was also performed. RESULTS: values < .05). These outcomes all remained statistically significant after adjusting for confounding variables. CONCLUSIONS: Mild thrombocytopenia prior to delivery is associated with a small increased chance of red blood cell transfusion, postpartum hemorrhage, uterotonic use, and the need for additional procedures postpartum.

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Publication Details

Journal
The Permanente Journal
Published
2026-06-16
DOI
https://doi.org/10.7812/tpp/25.147
Primary Topic
Maternal and fetal healthcare
Type
article
Field-Weighted Citation Impact
0.00
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article

Mild Thrombocytopenia at Admission to Labor and Delivery: Implications for Postpartum Hemorrhage

Rebecca J. Post, Brian Crosland, Richard Benoit, Adrian Lino Hernandez Lopez et al.
The Permanente Journal
Maternal and fetal healthcare
article

Mild Thrombocytopenia at Admission to Labor and Delivery: Implications for Postpartum Hemorrhage

Rebecca J. Post, Brian Crosland, Richard Benoit, Adrian Lino Hernandez Lopez, Kiran Magee, Joanie Chung, Judith Chung
article en

Abstract

BACKGROUND: Postpartum hemorrhage remains a leading cause of severe maternal morbidity and mortality. The association between mild thrombocytopenia and postpartum blood loss or red blood cell transfusion has not been well studied. OBJECTIVE: To evaluate whether mild thrombocytopenia at admission to labor and delivery is associated with increased rates of postpartum hemorrhage and packed red blood cell transfusion. STUDY DESIGN: or Mann-Whitney U test. A multivariable logistic regression was also performed. RESULTS: values < .05). These outcomes all remained statistically significant after adjusting for confounding variables. CONCLUSIONS: Mild thrombocytopenia prior to delivery is associated with a small increased chance of red blood cell transfusion, postpartum hemorrhage, uterotonic use, and the need for additional procedures postpartum.

The Permanente Journal
Kaiser Permanente (US), Oregon Health & Science University (US), University of California, Irvine (US), Kaiser Permanente Riverside Medical Center (US), Kaiser Permanente West Los Angeles Medical Center (US), Irvine University (US)
Decent work and economic growth
Openalex Percentile: Top 5%
Maternal and fetal healthcare
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