Pruritic Rash and Diarrhea in a Man with Chronic Alcohol Use Disorder

This report describes a 62-year-old male with long-term heavy alcohol consumption, who presented with pruritic, hyperpigmented scaly plaques on sun-exposed skin and recent non-bloody diarrhea. Skin histopathology showed psoriasiform hyperplasia and superficial perivascular lymphocytic infiltration, supporting the diagnosis of pellagra. The patient responded well to oral nicotinamide supplementation, with gradual and complete resolution of skin lesions within three months. This case emphasizes that alcoholic pellagra should be considered in patients with chronic alcoholism and typical photosensitive dermatitis.

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Publication Details

Journal
British Journal of Dermatology
Published
2026-06-16
DOI
https://doi.org/10.1093/bjd/ljag245
Primary Topic
Alcoholism and Thiamine Deficiency
Type
article
Field-Weighted Citation Impact
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article

Pruritic Rash and Diarrhea in a Man with Chronic Alcohol Use Disorder

Jiu‐Hong Li, Hong-Hao Hu
British Journal of Dermatology
Alcoholism and Thiamine Deficiency
article

Pruritic Rash and Diarrhea in a Man with Chronic Alcohol Use Disorder

Jiu‐Hong Li, Hong-Hao Hu
article en

Abstract

This report describes a 62-year-old male with long-term heavy alcohol consumption, who presented with pruritic, hyperpigmented scaly plaques on sun-exposed skin and recent non-bloody diarrhea. Skin histopathology showed psoriasiform hyperplasia and superficial perivascular lymphocytic infiltration, supporting the diagnosis of pellagra. The patient responded well to oral nicotinamide supplementation, with gradual and complete resolution of skin lesions within three months. This case emphasizes that alcoholic pellagra should be considered in patients with chronic alcoholism and typical photosensitive dermatitis.

British Journal of Dermatology
First Hospital of China Medical University (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN), China Medical University (CN)
Good health and well-being
Openalex Percentile: Top 7%
Alcoholism and Thiamine Deficiency
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