A Galvanostatic Strategy to Modulate ECL-RET in MnO <sub>2</sub> –Polypyrrole–Polyluminol Nanohybrids for Signal-On Sensing of Glutathione
NPs/PPy-PL/GCE gradually recovered upon incubation with the linearly increased concentration of GSH from 5 nM to 5 μM, and the calculated LOD and LOQ were 0.12 nM and 0.36 nM, respectively. The proposed sensor displays an excellent anti-interference ability and successfully demonstrates the sensing of GSH in human serum samples, which shows a good recovery percentage from 102% to 104%. The superior sensing performance of the proposed signal-on solid-state ECL-RET sensor methodology provides a promising potential for clinical diagnostics.
Authors
- Selvaraj Paramasivam
- Shanmugam Senthil Kumar (ORCID: https://orcid.org/0000-0002-7035-2920)
Institutions
- Central Electrochemical Research Institute (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Langmuir
- Published
- 2026-06-16
- DOI
- https://doi.org/10.1021/acs.langmuir.6c01219
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Council for Scientific and Industrial Research, South Africa
- Science and Engineering Research Board