Postpartum kidney assessment after hypertensive disorders of pregnancy: A practical framework for obstetric care

Hypertensive disorders of pregnancy, particularly pre-eclampsia, are recognized not only as major obstetric complications but also as early indicators of future maternal cardiovascular and renal risk. Despite this, postpartum care remains centered on blood pressure surveillance, whereas kidney assessment is not consistently incorporated into routine obstetric follow-up. This narrative review examines the renal implications of hypertensive disorders of pregnancy beyond delivery and translates guidance and observational evidence into a practical obstetric approach to postpartum kidney assessment. Available data indicate that a clinically meaningful subgroup of women have persistent renal abnormalities in the early postpartum period, most often as albuminuria or proteinuria rather than as overt reduction in estimated glomerular filtration rate. Reliance on blood pressure or serum creatinine alone may therefore fail to identify incomplete renal recovery, pregnancy-unmasked chronic kidney disease, or women requiring closer reassessment. We also emphasize pregnancy-associated acute kidney injury as a high-priority phenotype, operationalized by creatinine rise or oliguria using Kidney Disease: Improving Global Outcomes (KDIGO)-type criteria and interpreted against pregnancy-specific creatinine physiology. Patients meriting greater attention include those with severe or preterm disease, persistent hypertension, antenatal renal abnormalities, pregnancy-associated acute kidney injury, or relevant pre-existing comorbidity. We propose a feasible postpartum framework based on blood pressure measurement, serum creatinine with estimated glomerular filtration rate, and urinary assessment of albuminuria or proteinuria, with repeat testing or specialist evaluation guided by postpartum findings and clinical risk. Rather than creating a parallel nephrology pathway, this approach supports obstetric services in identifying women whose renal recovery may be incomplete.

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Publication Details

Journal
International Journal of Gynecology & Obstetrics
Published
2026-06-13
DOI
https://doi.org/10.1002/ijgo.71144
Primary Topic
Pregnancy and preeclampsia studies
Type
article
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article

Postpartum kidney assessment after hypertensive disorders of pregnancy: A practical framework for obstetric care

Nicole Seger Cunegatti, LM Brandão, Lucas Maciel de Almeida Corrêa, Juliana Zanella et al.
International Journal of Gynecology & Obstetrics
Pregnancy and preeclampsia studies
article

Postpartum kidney assessment after hypertensive disorders of pregnancy: A practical framework for obstetric care

Nicole Seger Cunegatti, LM Brandão, Lucas Maciel de Almeida Corrêa, Juliana Zanella, Gabriela Wander Fossati, Sicilia Lins Peixoto Arruda, Lara Reis Gomes de Mello Queiroz, Maria Eduarda Castro Gonçalves, Guilherme Diniz Ferreira
article en

Abstract

Hypertensive disorders of pregnancy, particularly pre-eclampsia, are recognized not only as major obstetric complications but also as early indicators of future maternal cardiovascular and renal risk. Despite this, postpartum care remains centered on blood pressure surveillance, whereas kidney assessment is not consistently incorporated into routine obstetric follow-up. This narrative review examines the renal implications of hypertensive disorders of pregnancy beyond delivery and translates guidance and observational evidence into a practical obstetric approach to postpartum kidney assessment. Available data indicate that a clinically meaningful subgroup of women have persistent renal abnormalities in the early postpartum period, most often as albuminuria or proteinuria rather than as overt reduction in estimated glomerular filtration rate. Reliance on blood pressure or serum creatinine alone may therefore fail to identify incomplete renal recovery, pregnancy-unmasked chronic kidney disease, or women requiring closer reassessment. We also emphasize pregnancy-associated acute kidney injury as a high-priority phenotype, operationalized by creatinine rise or oliguria using Kidney Disease: Improving Global Outcomes (KDIGO)-type criteria and interpreted against pregnancy-specific creatinine physiology. Patients meriting greater attention include those with severe or preterm disease, persistent hypertension, antenatal renal abnormalities, pregnancy-associated acute kidney injury, or relevant pre-existing comorbidity. We propose a feasible postpartum framework based on blood pressure measurement, serum creatinine with estimated glomerular filtration rate, and urinary assessment of albuminuria or proteinuria, with repeat testing or specialist evaluation guided by postpartum findings and clinical risk. Rather than creating a parallel nephrology pathway, this approach supports obstetric services in identifying women whose renal recovery may be incomplete.

International Journal of Gynecology & Obstetrics
Universidade Federal do Rio Grande do Sul (BR), Faculdade de Medicina de São José do Rio Preto (BR), Pontifícia Universidade Católica do Paraná (BR), Universidade Federal de Santa Catarina (BR), Centro Universitário do Norte (BR), Faculdade de Ciências Médicas de Minas Gerais (BR), Centro Universitário Cesmac (BR), Universidade Federal de São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 5%
Pregnancy and preeclampsia studies
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