Performance of large language models for ophthalmic literature retrieval

Large language models (LLMs) such as ChatGPT, are increasingly used to search the literature and answer focused clinical questions. However, evidence on their reliability for study retrieval remains limited, particularly in Ophthalmology, where conditions are rare, terminology is nuanced, and niche management continually evolves [ 1 ]. Reports of hallucinated references in earlier-generation models underscores the need for contemporary, domain-specific evaluation [ 2 ].

Authors

Institutions

Publication Details

Journal
Eye
Published
2026-06-12
DOI
https://doi.org/10.1038/s41433-026-04586-y
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Performance of large language models for ophthalmic literature retrieval

Ayushi Agarwal, Weng Onn Chan, Jai Paris, Dinesh Selva et al.
Eye
Artificial Intelligence in Healthcare and Education
article

Performance of large language models for ophthalmic literature retrieval

Ayushi Agarwal, Weng Onn Chan, Jai Paris, Dinesh Selva, Oliver Kleinig
article en

Abstract

Large language models (LLMs) such as ChatGPT, are increasingly used to search the literature and answer focused clinical questions. However, evidence on their reliability for study retrieval remains limited, particularly in Ophthalmology, where conditions are rare, terminology is nuanced, and niche management continually evolves [ 1 ]. Reports of hallucinated references in earlier-generation models underscores the need for contemporary, domain-specific evaluation [ 2 ].

Eye
Royal Adelaide Hospital (AU), The University of Adelaide (AU)
Quality Education
Openalex Percentile: Top 8%
Artificial Intelligence in Healthcare and Education
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.