An In Situ-Generated Near-Infrared Chemiluminescent Nanoprobe for High-Contrast Lymph Node Mapping and Tumor-Guided Surgery
materials further improved the probe's in vivo stability and brightness, enabling clear visualization of lymph nodes and tumor-guided surgery. Overall, this study proposes a single-molecule strategy for direct NIR chemiluminescent emission that combines high safety with broad applicability, offering a promising approach for developing low-toxicity, high-reliability chemiluminescent imaging platforms.
Authors
- Heqing Yi (ORCID: https://orcid.org/0000-0002-5164-4821)
- Xue‐Qiang Wang (ORCID: https://orcid.org/0000-0003-1631-9158)
- Yiren Hu (ORCID: https://orcid.org/0000-0002-5054-9734)
- S H E N G H Zhou
- F H Zhao
- Yun Zhang
Institutions
- Hunan University (CN)
- Chinese Academy of Sciences (CN)
- Wenzhou Medical University (CN)
- Zhejiang Cancer Hospital (CN)
- Wenzhou City People's Hospital (CN)
Publication Details
- Journal
- Analytical Chemistry
- Published
- 2026-06-12
- DOI
- https://doi.org/10.1021/acs.analchem.6c01497
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese Academy of Sciences
- Science and Technology Program of Zhejiang Province