Ocular Loiasis in Morocco: A Case Report From a Non-endemic Area

Loiasis is a parasitic infection caused by the filarial nematode Loa loa, endemic to Central and West Africa. Its occurrence in non-endemic regions such as Morocco is rare and may pose a diagnostic challenge. We report the case of a Moroccan patient presenting with an intermittent sensation of a mobile foreign body in the eye, associated with redness and photophobia. The patient reported no recent travel to endemic regions but had close contact with individuals originating from Cameroon, a loiasis-endemic area, raising questions regarding possible indirect or remote exposure. Following several consultations, spontaneous exteriorization of a subconjunctival worm was observed. The diagnosis was supported by clinical observation of the subconjunctival worm, blood parasitological testing demonstrating microfilaremia, and the presence of Calabar swellings. The patient was treated with ivermectin followed by albendazole, resulting in complete clinical recovery without recurrence during follow-up. This case highlights the importance of considering loiasis in the differential diagnosis of atypical ocular symptoms, even in non-endemic settings, and underscores the value of multidisciplinary collaboration for timely diagnosis and appropriate management.

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Publication Details

Journal
Cureus
Published
2026-06-12
DOI
https://doi.org/10.7759/cureus.110716
Primary Topic
Parasitic Diseases Research and Treatment
Type
article
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article

Ocular Loiasis in Morocco: A Case Report From a Non-endemic Area

Houda Safwate, Amine Razzak, M. Elbelhadji, Hala Ait Amar et al.
Cureus
Parasitic Diseases Research and Treatment
article

Ocular Loiasis in Morocco: A Case Report From a Non-endemic Area

Houda Safwate, Amine Razzak, M. Elbelhadji, Hala Ait Amar, Mohamed Bouazza
article en

Abstract

Loiasis is a parasitic infection caused by the filarial nematode Loa loa, endemic to Central and West Africa. Its occurrence in non-endemic regions such as Morocco is rare and may pose a diagnostic challenge. We report the case of a Moroccan patient presenting with an intermittent sensation of a mobile foreign body in the eye, associated with redness and photophobia. The patient reported no recent travel to endemic regions but had close contact with individuals originating from Cameroon, a loiasis-endemic area, raising questions regarding possible indirect or remote exposure. Following several consultations, spontaneous exteriorization of a subconjunctival worm was observed. The diagnosis was supported by clinical observation of the subconjunctival worm, blood parasitological testing demonstrating microfilaremia, and the presence of Calabar swellings. The patient was treated with ivermectin followed by albendazole, resulting in complete clinical recovery without recurrence during follow-up. This case highlights the importance of considering loiasis in the differential diagnosis of atypical ocular symptoms, even in non-endemic settings, and underscores the value of multidisciplinary collaboration for timely diagnosis and appropriate management.

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Ocular Loiasis in Morocco: A Case Report From a Non-endemic Area — Houda Safwate, Amine Razzak, et al. · Cureus (2026) | TGRS Research Map | TGRS