ONE-STAGE DELAYED BLADDER EXSTROPHY CLOSURE COMBINED WITH KELLY REPAIR: Early outcomes following the 100-case milestone

PURPOSE: To evaluate bladder dehiscence after one-stage delayed closure of bladder/cloacal exstrophy combining bladder plate closure with Kelly procedure, with or without osteotomy. MATERIALS AND METHODS: Multicenter retrospective study of children with bladder exstrophy or cloacal exstrophy who underwent single-stage closure with Kelly mobilization (October 2015-October 2025), by one surgical team, in France and tertiary centers abroad. The primary endpoint was bladder dehiscence within 3 months. Secondary endpoints were early (<3 months) complications. Outcomes were analyzed separately for primary repairs and complex cases. RESULTS AND CONCLUSION: muscles midline transposition was the only independent prognostic factor of wound complications (OR 4.47 [1.22-16.37] p= .02).Single-stage delayed closure combined with Kelly mobilization allows reliable bladder closure with no early dehiscence in bladder/cloacal exstrophy. Early morbidity rate was <20%, with predominantly low-grade complications. When pubic approximation was difficult, osteotomies or fascial flaps appeared to offer better early parietal outcomes than rectus muscles transposition.

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Publication Details

Journal
The Journal of Urology
Published
2026-06-12
DOI
https://doi.org/10.1097/ju.0000000000005167
Primary Topic
Gallbladder and Bile Duct Disorders
Type
article
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article

ONE-STAGE DELAYED BLADDER EXSTROPHY CLOSURE COMBINED WITH KELLY REPAIR: Early outcomes following the 100-case milestone

Olivier Abbo, Luke Harper, Nicolas Kalfa, Alice Faure et al.
The Journal of Urology
Gallbladder and Bile Duct Disorders
article

ONE-STAGE DELAYED BLADDER EXSTROPHY CLOSURE COMBINED WITH KELLY REPAIR: Early outcomes following the 100-case milestone

Olivier Abbo, Luke Harper, Nicolas Kalfa, Alice Faure, R. Moog, A el Ghoneimi, Hortense Alliot, Alfredo Berrettini, D. Demède, Marc‐David Leclair, Xavier Delforge, T. Loubersac, Thomas Blanc, Sajid Sultan, Pedro-Jose Lopez, Jovelinho LEAO
article en

Abstract

PURPOSE: To evaluate bladder dehiscence after one-stage delayed closure of bladder/cloacal exstrophy combining bladder plate closure with Kelly procedure, with or without osteotomy. MATERIALS AND METHODS: Multicenter retrospective study of children with bladder exstrophy or cloacal exstrophy who underwent single-stage closure with Kelly mobilization (October 2015-October 2025), by one surgical team, in France and tertiary centers abroad. The primary endpoint was bladder dehiscence within 3 months. Secondary endpoints were early (<3 months) complications. Outcomes were analyzed separately for primary repairs and complex cases. RESULTS AND CONCLUSION: muscles midline transposition was the only independent prognostic factor of wound complications (OR 4.47 [1.22-16.37] p= .02).Single-stage delayed closure combined with Kelly mobilization allows reliable bladder closure with no early dehiscence in bladder/cloacal exstrophy. Early morbidity rate was <20%, with predominantly low-grade complications. When pubic approximation was difficult, osteotomies or fascial flaps appeared to offer better early parietal outcomes than rectus muscles transposition.

The Journal of Urology
Hôpital Necker-Enfants Malades (FR), Sindh Institute of Urology and Transplantation (PK), Centre Hospitalier Universitaire de Nantes (FR), Centre Hospitalier Universitaire de Toulouse (FR), Ospedale Maggiore (IT), Centre Hospitalier Universitaire Amiens-Picardie (FR), Hospices Civils de Lyon (FR), Laboratoire National de Référence (MA), Hôpital Pellegrin (FR), Production Development Corporation (CL), Hôpital Robert-Debré (FR), Hospital Materno-Infantil (ES), Hôpital Lapeyronie (FR), Hôpital des Enfants (FR), Hôpital de la Timone (FR), Nantes Université (FR)
Openalex Percentile: Top 6%
Gallbladder and Bile Duct Disorders
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