Multidisciplinary Dental Rehabilitation in an Adult with Noonan Syndrome: A Case Report

Noonan syndrome (NS) is a rare autosomal dominant disorder characterized by distinctive craniofacial features, congenital heart disease, bleeding disorders, and variable cognitive impairment. Oral manifestations may include malocclusion, delayed tooth eruption, enamel defects, and dental anomalies. This report describes the multidisciplinary management of a 34-year-old man with NS presenting with dental trauma, unaesthetic anterior teeth, and functional concerns. Management involved surgical extractions, endodontic treatment, and prosthetic rehabilitation, coordinated with cardiology and hematology teams to minimize systemic risks. Individualized treatment planning, behavioral adaptations, and tailored hemostatic strategies facilitated safe dental rehabilitation. This case highlights the importance of interprofessional collaboration and risk-adapted dental care in patients with complex systemic conditions.

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Publication Details

Journal
Cureus
Published
2026-06-12
DOI
https://doi.org/10.7759/cureus.110748
Primary Topic
Protein Tyrosine Phosphatases
Type
article
Field-Weighted Citation Impact
0.00
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article

Multidisciplinary Dental Rehabilitation in an Adult with Noonan Syndrome: A Case Report

Carina Mehanna Zogheib, Carla Zogheib, Samar A Bou Jaoude, Maha H Daou et al.
Cureus
Protein Tyrosine Phosphatases
article

Multidisciplinary Dental Rehabilitation in an Adult with Noonan Syndrome: A Case Report

Carina Mehanna Zogheib, Carla Zogheib, Samar A Bou Jaoude, Maha H Daou, Nawal M El-Baba
article en

Abstract

Noonan syndrome (NS) is a rare autosomal dominant disorder characterized by distinctive craniofacial features, congenital heart disease, bleeding disorders, and variable cognitive impairment. Oral manifestations may include malocclusion, delayed tooth eruption, enamel defects, and dental anomalies. This report describes the multidisciplinary management of a 34-year-old man with NS presenting with dental trauma, unaesthetic anterior teeth, and functional concerns. Management involved surgical extractions, endodontic treatment, and prosthetic rehabilitation, coordinated with cardiology and hematology teams to minimize systemic risks. Individualized treatment planning, behavioral adaptations, and tailored hemostatic strategies facilitated safe dental rehabilitation. This case highlights the importance of interprofessional collaboration and risk-adapted dental care in patients with complex systemic conditions.

Cureus
Openalex Percentile: Top 10%
Protein Tyrosine Phosphatases
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