Management of Sepsis-Induced Coagulopathy and Septic Pulmonary Embolism Secondary to Severe Maxillofacial Space Infection

Poorly controlled severe maxillofacial space infection can easily lead to sepsis, which may further induce sepsis-induced coagulopathy (SIC), septic shock, and septic pulmonary embolism (SPE). Key strategies include: managing SIC with airway bleeding; implementing precise fluid resuscitation for septic shock while minimizing cardiovascular risks; ensuring safe anticoagulation therapy for SPE under high bleeding risk; and providing systemic anti-infection treatment along with meticulous care of the primary lesion. This article reports a case of a patient with severe maxillofacial space infection secondary to SIC, septic shock, and SPE.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2026-06-12
DOI
https://doi.org/10.1097/scs.0000000000013045
Primary Topic
Otolaryngology and Infectious Diseases
Type
article
Field-Weighted Citation Impact
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article

Management of Sepsis-Induced Coagulopathy and Septic Pulmonary Embolism Secondary to Severe Maxillofacial Space Infection

Guofeng Ye, Leiwen Tang, Yi Tl, Hongyan Sun et al.
Journal of Craniofacial Surgery
Otolaryngology and Infectious Diseases
article

Management of Sepsis-Induced Coagulopathy and Septic Pulmonary Embolism Secondary to Severe Maxillofacial Space Infection

Guofeng Ye, Leiwen Tang, Yi Tl, Hongyan Sun, Qiaomei Zhao, Yueying Jiang
article en

Abstract

Poorly controlled severe maxillofacial space infection can easily lead to sepsis, which may further induce sepsis-induced coagulopathy (SIC), septic shock, and septic pulmonary embolism (SPE). Key strategies include: managing SIC with airway bleeding; implementing precise fluid resuscitation for septic shock while minimizing cardiovascular risks; ensuring safe anticoagulation therapy for SPE under high bleeding risk; and providing systemic anti-infection treatment along with meticulous care of the primary lesion. This article reports a case of a patient with severe maxillofacial space infection secondary to SIC, septic shock, and SPE.

Journal of Craniofacial Surgery
Second Affiliated Hospital of Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 6%
Otolaryngology and Infectious Diseases
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Management of Sepsis-Induced Coagulopathy and Septic Pulmonary Embolism Secondary to Severe Maxillofacial Space Infection — Guofeng Ye, Leiwen Tang, et al. · Journal of Craniofacial Surgery (2026) | TGRS Research Map | TGRS