Effects of a Novel Audio Mix Integrating Music, Mindfulness, Muscle Relaxation, and Prayer on Dialysis Adequacy and Holistic Health in Patients Undergoing Haemodialysis

Objectives Chronic kidney disease (CKD) is one of the major global health challenges, as patients receiving haemodialysis often experience reduced quality of life due to various factors affecting physical, psychological, and spiritual wellness. While previous research has mainly studied isolated interventions such as music therapy, mindfulness, or muscle relaxation to improve holistic health, evidence on an integrated approach is less explored. In this study, a ‘novel audio mix’ that combines music, mindfulness with muscle relaxation, and prayer was evaluated for its effects on dialysis adequacy and holistic health among patients undergoing haemodialysis. Material and Methods In this study, a quasi-experimental, pretest-posttest, control group design was adopted. Thirty patients in total were recruited from two dialysis units through purposive sampling. They were assigned to two groups: a) intervention (n = 15) and b) control (n = 15). The intervention group listened to the ‘novel audio mix’ three times a week for 12 weeks, during the haemodialysis, while the control group received routine haemodialysis. The study collected demographic data, including age, sex, and educational qualification. Clinical data, such as duration of illness, associated comorbidities, and medication history, were also recorded. Dialysis adequacy was assessed using single-pool Kt/V, and holistic health status was measured using the holistic health status questionnaire (HHSQ-45 item). Statistical analysis involved repeated measures analysis of variance (ANOVA) with significance set at p <0.05. Results The average age of study subjects was 46.2 ± 7.3 years, and most of them were male. The majority of them were on haemodialysis for 1-5 years with associated comorbidity, hypertension, and were on antihypertensive medications. The intervention group showed a significant improvement in holistic health status (F = 132.19, p <0.001), and minor improvements in dialysis adequacy (F = 0.331, p = 0.803) were observed over 12 weeks. In contrast, the control group showed minimal and statistically insignificant changes. Conclusion This study highlights that a ‘novel audio mix’ integrating music, mindfulness, muscle relaxation, and prayer may significantly improve holistic health status among patients undergoing haemodialysis; however, its potential benefit on dialysis adequacy was not statistically significant. Incorporating such complementary audio-based interventions into routine dialysis care may enhance patients’ overall well-being.