Multi-modal deep temporal adversarial network based on multi-head self-attention for breast cancer survival prediction

Breast cancer is the most commonly diagnosed malignant tumor among women worldwide. Since breast cancer is highly heterogeneous, it is difficult to determine the cancer type and treatment plan. Accurate prognostic prediction is crucial for breast cancer management. However, existing prediction methods often overlook survival-related information, affecting multi-modal feature extraction and fusion. To address these limitations, we propose a novel Multi-modal Deep Temporal Adversarial Network (MDTAN) designed to predict breast cancer prognosis with greater accuracy. We evaluated our model on the METABRIC dataset using various metrics. Compared with other methods, our model shows superior prediction performance.

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Publication Details

Journal
Computer Methods in Biomechanics & Biomedical Engineering
Published
2026-06-12
DOI
https://doi.org/10.1080/10255842.2026.2682550
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
0.00

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article

Multi-modal deep temporal adversarial network based on multi-head self-attention for breast cancer survival prediction

Yuan Han, Hongzhen Xu, Zongxiang Huang, Haoyu Xue
Computer Methods in Biomechanics & Biomedical Engineering
AI in cancer detection
article

Multi-modal deep temporal adversarial network based on multi-head self-attention for breast cancer survival prediction

Yuan Han, Hongzhen Xu, Zongxiang Huang, Haoyu Xue
article en

Abstract

Breast cancer is the most commonly diagnosed malignant tumor among women worldwide. Since breast cancer is highly heterogeneous, it is difficult to determine the cancer type and treatment plan. Accurate prognostic prediction is crucial for breast cancer management. However, existing prediction methods often overlook survival-related information, affecting multi-modal feature extraction and fusion. To address these limitations, we propose a novel Multi-modal Deep Temporal Adversarial Network (MDTAN) designed to predict breast cancer prognosis with greater accuracy. We evaluated our model on the METABRIC dataset using various metrics. Compared with other methods, our model shows superior prediction performance.

Computer Methods in Biomechanics & Biomedical Engineering
East China University of Science and Technology (CN), Foshan University (CN), East China University of Technology (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 4%
AI in cancer detection
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Multi-modal deep temporal adversarial network based on multi-head self-attention for breast cancer survival prediction — Yuan Han, Hongzhen Xu, et al. · Computer Methods in Biomechanics & Biomedical Engineering (2026) | TGRS Research Map | TGRS