Radiological management of reversible cerebral vasoconstriction syndrome (RCVS) in France: a national multicenter survey

BACKGROUND AND PURPOSE: The management of reversible cerebral vasoconstriction syndrome (RCVS) lacks formal imaging guidelines, resulting in variable diagnostic and follow-up strategies. This study aimed to evaluate contemporary radiological practices for RCVS across French academic centers and to derive a pragmatic imaging pathway based on observed consensus and literature data. MATERIALS AND METHODS: A national, multicenter, cross-sectional survey was conducted between February 2025 and January 2026 among French academic neuroradiology centers. An online questionnaire assessed first-line imaging modalities, protocol components, confirmatory strategies, and long-term follow-up practices as implemented during the 2024 calendar year. Data were analyzed descriptively. RESULTS: Twenty-six centers responded (87%, 26/30). CT angiography was the preferred first-line modality (77%). MRI was universally incorporated, with consistent use of a core protocol (diffusion-weighted imaging, fluid-attenuated inversion recovery, susceptibility-weighted imaging, and MR angiography), while advanced sequences showed marked variability. After a positive initial examination, 54% of centers performed confirmatory imaging, most commonly MRI. In cases of high clinical suspicion despite negative initial imaging, 69% performed follow-up imaging, with heterogeneous timing. Long-term imaging to document reversibility was performed by 85% of centers. Digital subtraction angiography was reserved for selected cases and was not performed for therapeutic purposes. CONCLUSIONS: The radiological management of reversible cerebral vasoconstriction syndrome in France demonstrates a strong consensus regarding initial emergency imaging but substantial heterogeneity in confirmatory and follow-up strategies. Based on survey findings and published data on the temporal dynamics of reversible cerebral vasoconstriction syndrome, we propose a pragmatic imaging pathway intended as a structured synthesis rather than a formal recommendation. Prospective validation is warranted.

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Journal
American Journal of Neuroradiology
Published
2026-06-12
DOI
https://doi.org/10.3174/ajnr.a9474
Primary Topic
Neurological Complications and Syndromes
Type
article
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article

Radiological management of reversible cerebral vasoconstriction syndrome (RCVS) in France: a national multicenter survey

Quentin Holay, Thomas Samoyeau, Guillaume Bellanger, Paolo Pagano et al.
American Journal of Neuroradiology
Neurological Complications and Syndromes
article

Radiological management of reversible cerebral vasoconstriction syndrome (RCVS) in France: a national multicenter survey

Quentin Holay, Thomas Samoyeau, Guillaume Bellanger, Paolo Pagano, Guillaume Charbonnier, François Zhu, Julien Burel, Alexis Guédon, Thibault Agripnidis, Claire Boutet, Julien Boucherit, Géraud Forestier, Baptiste Donnard, Jonathan Cortese, Aboubacar Keita, Joachim Bousquet, Benoît Dimitrov, Victor Dumas, Vincent L’allinec, Julien Ognard, Augustin Lecler, Aymeric Rouchaud, Gaultier Marnat, Lucile Hausser, Luca Scarcia, Eimad Shotar, Guillaume Tessier
article en

Abstract

BACKGROUND AND PURPOSE: The management of reversible cerebral vasoconstriction syndrome (RCVS) lacks formal imaging guidelines, resulting in variable diagnostic and follow-up strategies. This study aimed to evaluate contemporary radiological practices for RCVS across French academic centers and to derive a pragmatic imaging pathway based on observed consensus and literature data. MATERIALS AND METHODS: A national, multicenter, cross-sectional survey was conducted between February 2025 and January 2026 among French academic neuroradiology centers. An online questionnaire assessed first-line imaging modalities, protocol components, confirmatory strategies, and long-term follow-up practices as implemented during the 2024 calendar year. Data were analyzed descriptively. RESULTS: Twenty-six centers responded (87%, 26/30). CT angiography was the preferred first-line modality (77%). MRI was universally incorporated, with consistent use of a core protocol (diffusion-weighted imaging, fluid-attenuated inversion recovery, susceptibility-weighted imaging, and MR angiography), while advanced sequences showed marked variability. After a positive initial examination, 54% of centers performed confirmatory imaging, most commonly MRI. In cases of high clinical suspicion despite negative initial imaging, 69% performed follow-up imaging, with heterogeneous timing. Long-term imaging to document reversibility was performed by 85% of centers. Digital subtraction angiography was reserved for selected cases and was not performed for therapeutic purposes. CONCLUSIONS: The radiological management of reversible cerebral vasoconstriction syndrome in France demonstrates a strong consensus regarding initial emergency imaging but substantial heterogeneity in confirmatory and follow-up strategies. Based on survey findings and published data on the temporal dynamics of reversible cerebral vasoconstriction syndrome, we propose a pragmatic imaging pathway intended as a structured synthesis rather than a formal recommendation. Prospective validation is warranted.

American Journal of Neuroradiology
Centre National de la Recherche Scientifique (FR), Assistance Publique – Hôpitaux de Paris (FR), Hôpital de la Timone (FR)
Good health and well-being
Openalex Percentile: Top 6%
Neurological Complications and Syndromes
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