Radiological management of reversible cerebral vasoconstriction syndrome (RCVS) in France: a national multicenter survey
BACKGROUND AND PURPOSE: The management of reversible cerebral vasoconstriction syndrome (RCVS) lacks formal imaging guidelines, resulting in variable diagnostic and follow-up strategies. This study aimed to evaluate contemporary radiological practices for RCVS across French academic centers and to derive a pragmatic imaging pathway based on observed consensus and literature data. MATERIALS AND METHODS: A national, multicenter, cross-sectional survey was conducted between February 2025 and January 2026 among French academic neuroradiology centers. An online questionnaire assessed first-line imaging modalities, protocol components, confirmatory strategies, and long-term follow-up practices as implemented during the 2024 calendar year. Data were analyzed descriptively. RESULTS: Twenty-six centers responded (87%, 26/30). CT angiography was the preferred first-line modality (77%). MRI was universally incorporated, with consistent use of a core protocol (diffusion-weighted imaging, fluid-attenuated inversion recovery, susceptibility-weighted imaging, and MR angiography), while advanced sequences showed marked variability. After a positive initial examination, 54% of centers performed confirmatory imaging, most commonly MRI. In cases of high clinical suspicion despite negative initial imaging, 69% performed follow-up imaging, with heterogeneous timing. Long-term imaging to document reversibility was performed by 85% of centers. Digital subtraction angiography was reserved for selected cases and was not performed for therapeutic purposes. CONCLUSIONS: The radiological management of reversible cerebral vasoconstriction syndrome in France demonstrates a strong consensus regarding initial emergency imaging but substantial heterogeneity in confirmatory and follow-up strategies. Based on survey findings and published data on the temporal dynamics of reversible cerebral vasoconstriction syndrome, we propose a pragmatic imaging pathway intended as a structured synthesis rather than a formal recommendation. Prospective validation is warranted.
Authors
- Quentin Holay (ORCID: https://orcid.org/0000-0002-3781-4628)
- Thomas Samoyeau (ORCID: https://orcid.org/0000-0002-7259-7876)
- Guillaume Bellanger (ORCID: https://orcid.org/0000-0002-3642-904X)
- Paolo Pagano (ORCID: https://orcid.org/0000-0001-5821-2653)
- Guillaume Charbonnier (ORCID: https://orcid.org/0000-0002-4425-3849)
- François Zhu (ORCID: https://orcid.org/0000-0003-3838-9608)
- Julien Burel (ORCID: https://orcid.org/0000-0001-8726-265X)
- Alexis Guédon (ORCID: https://orcid.org/0000-0002-1309-235X)
- Thibault Agripnidis (ORCID: https://orcid.org/0000-0003-2772-2954)
- Claire Boutet (ORCID: https://orcid.org/0000-0001-9850-4124)
- Julien Boucherit (ORCID: https://orcid.org/0009-0000-0824-3128)
- Géraud Forestier (ORCID: https://orcid.org/0000-0003-4797-9693)
- Baptiste Donnard (ORCID: https://orcid.org/0009-0003-2427-2625)
- Jonathan Cortese
- Aboubacar Keita
- Joachim Bousquet
- Benoît Dimitrov
- Victor Dumas
- Vincent L’allinec
- Julien Ognard
- Augustin Lecler
- Aymeric Rouchaud
- Gaultier Marnat
- Lucile Hausser
- Luca Scarcia
- Eimad Shotar
- Guillaume Tessier
Institutions
- Centre National de la Recherche Scientifique (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital de la Timone (FR)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2026-06-12
- DOI
- https://doi.org/10.3174/ajnr.a9474
- Primary Topic
- Neurological Complications and Syndromes
- Type
- article
- Field-Weighted Citation Impact
- 0.00