The 9th Edition of the <scp>UICC TNM</scp> Classification of Malignant Tumours: Updates and Rationale for Change

The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s. Due to the expanding medical knowledge of tumour behaviour and advances in imaging, pathology and therapeutic options, TNM has been updated in collaboration with the American Joint Committee on Cancer (AJCC), the International Association for the study of Lung Cancer (IASLC) and the Federation Internationale de Gynecologie et d'Obstetrique (FIGO) on a regular basis. The 9th edition of the UICC TNM Classification of Malignant Tumours has recently been published. This review summarized the changes between the 8th and 9th edition. The evidence basis used for revision is described and referenced, with a focus on the changes in head and neck and lung cancers.

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Journal
International Journal of Cancer
Published
2026-06-09
DOI
https://doi.org/10.1002/ijc.70561
Primary Topic
Head and Neck Cancer Studies
Type
article
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article

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

James D. Brierley, Sicong Huang, M GOSPODAROWICZ, B. O’Sullivan et al.
International Journal of Cancer
Head and Neck Cancer Studies
article

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

James D. Brierley, Sicong Huang, M GOSPODAROWICZ, B. O’Sullivan, Liesbet J. Van Eycken, Meredith E. Giuliani, Anne W. Lee, Hisao Asamura, Brian A. Rous
article en

Abstract

The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s. Due to the expanding medical knowledge of tumour behaviour and advances in imaging, pathology and therapeutic options, TNM has been updated in collaboration with the American Joint Committee on Cancer (AJCC), the International Association for the study of Lung Cancer (IASLC) and the Federation Internationale de Gynecologie et d'Obstetrique (FIGO) on a regular basis. The 9th edition of the UICC TNM Classification of Malignant Tumours has recently been published. This review summarized the changes between the 8th and 9th edition. The evidence basis used for revision is described and referenced, with a focus on the changes in head and neck and lung cancers.

International Journal of Cancer
University of Toronto (CA), Keio University (JP), Cambridge University Hospitals NHS Foundation Trust (GB), Princess Margaret Cancer Centre (CA), Centre Hospitalier de l’Université de Montréal (CA), University of Hong Kong (HK)
Good health and well-being, Partnerships for the goals
Openalex Percentile: Top 5%
Head and Neck Cancer Studies
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The 9th Edition of the <scp>UICC TNM</scp> Classification of Malignant Tumours: Updates and Rationale for Change — James D. Brierley, Sicong Huang, et al. · International Journal of Cancer (2026) | TGRS Research Map | TGRS