In adult patients with suspected sepsis, is adjunct resuscitation with human albumin solution associated with improved patient-oriented outcomes?

A short systematic review was undertaken to answer the following three-part question: in adult patients with suspected sepsis, is adjunct resuscitation with human albumin solution (HAS) associated with improved patient-oriented outcomes? A systematic keyword search of EMBASE, MEDLINE, Cochrane and Google Scholar databases returned three relevant papers which were subsequently used in the final analysis. The author, year, country of publication, patient group studied, study type, key findings and study weaknesses are tabulated. The results suggest that resuscitation with HAS is not recommended in the emergency department in suspected sepsis and larger studies are required to address this clinical question.

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Publication Details

Journal
Emergency Medicine Journal
Published
2026-06-09
DOI
https://doi.org/10.1136/emermed-2026-216135
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
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article

In adult patients with suspected sepsis, is adjunct resuscitation with human albumin solution associated with improved patient-oriented outcomes?

Harriet Phelan, Cameron Davie
Emergency Medicine Journal
Trauma, Hemostasis, Coagulopathy, Resuscitation
article

In adult patients with suspected sepsis, is adjunct resuscitation with human albumin solution associated with improved patient-oriented outcomes?

Harriet Phelan, Cameron Davie
article en

Abstract

A short systematic review was undertaken to answer the following three-part question: in adult patients with suspected sepsis, is adjunct resuscitation with human albumin solution (HAS) associated with improved patient-oriented outcomes? A systematic keyword search of EMBASE, MEDLINE, Cochrane and Google Scholar databases returned three relevant papers which were subsequently used in the final analysis. The author, year, country of publication, patient group studied, study type, key findings and study weaknesses are tabulated. The results suggest that resuscitation with HAS is not recommended in the emergency department in suspected sepsis and larger studies are required to address this clinical question.

Emergency Medicine Journal
Shrewsbury and Telford Hospital NHS Trust (GB)
Openalex Percentile: Top 6%
Trauma, Hemostasis, Coagulopathy, Resuscitation
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