Diagnostic Challenges of Leprosy in Primary Health Care: A Brazilian Case Report

Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Although it progresses slowly, it has a high potential to cause physical disabilities when diagnosis and treatment are delayed. Brazil remains the second-highest contributor to the global burden of the disease. This study reports the case of a 37-year-old man who was diagnosed with leprosy five months after the onset of symptoms. During this period, several alternative diagnostic hypotheses were considered, resulting in a delay in initiating appropriate treatment and illustrating the diagnostic challenges associated with the disease. This case highlights the importance of maintaining a high index of suspicion for leprosy, particularly in endemic settings. Effective care coordination within primary health care plays a crucial role in the timely diagnosis, treatment adherence, and prevention of disabling sequelae associated with the disease.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-06-09
DOI
https://doi.org/10.5281/zenodo.20612221
Primary Topic
Leprosy Research and Treatment
Type
preprint
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preprint

Diagnostic Challenges of Leprosy in Primary Health Care: A Brazilian Case Report

Rafaela Castellar Corte, Keller Keller, Thiago Paes de Barros De Luccia
Zenodo (CERN European Organization for Nuclear Research)
Leprosy Research and Treatment
preprint

Diagnostic Challenges of Leprosy in Primary Health Care: A Brazilian Case Report

Rafaela Castellar Corte, Keller Keller, Thiago Paes de Barros De Luccia
preprint en

Abstract

Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Although it progresses slowly, it has a high potential to cause physical disabilities when diagnosis and treatment are delayed. Brazil remains the second-highest contributor to the global burden of the disease. This study reports the case of a 37-year-old man who was diagnosed with leprosy five months after the onset of symptoms. During this period, several alternative diagnostic hypotheses were considered, resulting in a delay in initiating appropriate treatment and illustrating the diagnostic challenges associated with the disease. This case highlights the importance of maintaining a high index of suspicion for leprosy, particularly in endemic settings. Effective care coordination within primary health care plays a crucial role in the timely diagnosis, treatment adherence, and prevention of disabling sequelae associated with the disease.

Zenodo (CERN European Organization for Nuclear Research)
Faculdade São Leopoldo Mandic (BR)
Leprosy Research and Treatment
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Diagnostic Challenges of Leprosy in Primary Health Care: A Brazilian Case Report — Rafaela Castellar Corte, Keller Keller, et al. · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS