Water-Soluble Viscosity-Activated Molecular Rotor for <i>In Situ</i> Imaging of Liver Damage in the NIR-II Window
-induced fibrosis, and diet/drug-induced steatosis. Signal changes correlate with standard biochemical and histological markers and decrease after treatment. These findings identify PEGylated NIR-II molecular rotors as promising tools for noninvasive, real-time mechanism-based assessment of liver disease.
Authors
- Hualong Fu (ORCID: https://orcid.org/0000-0002-7197-8087)
- J Y Zhang
- Jiaming Guo (ORCID: https://orcid.org/0000-0003-3144-589X)
- Kaixiang Zhou (ORCID: https://orcid.org/0000-0003-4210-6711)
- Yufei Qin (ORCID: https://orcid.org/0000-0001-8873-1825)
- Zhong Guo (ORCID: https://orcid.org/0000-0002-4443-9360)
- Mengchao Cui (ORCID: https://orcid.org/0000-0002-3488-7864)
- Huiyan Zhang (ORCID: https://orcid.org/0000-0003-3406-8954)
- Gao Y (ORCID: https://orcid.org/0000-0001-6502-9910)
- Yingnan Zeng
Institutions
- Beijing Normal University (CN)
- Kementerian Pendidikan Malaysia (MY)
Publication Details
- Journal
- ACS Sensors
- Published
- 2026-06-09
- DOI
- https://doi.org/10.1021/acssensors.6c00771
- Primary Topic
- Molecular Sensors and Ion Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Beijing Normal University
- Beijing Municipal Natural Science Foundation
- Basic and Applied Basic Research Foundation of Guangdong Province