A review on thymoquinone: a promising therapeutic molecule in Alzheimer's

accumulation, modulate tau-related pathology, and improve neuronal survival and cognitive performance in several AD models. The review also discusses delivery strategies to improve the bioavailability and brain targeting of TQ, including nanoformulation-based approaches. Although the available pre-clinical findings support the therapeutic promise of TQ. The well-designed clinical studies are required to establish its efficacy, safety, optimal dosing, and long-term translational value in treating AD.