Reductive cross-coupling reaction between <i>β</i> -bromostyrenes and alkynes using Cp2ZrF2 and a palladium catalyst
Abstract Stereoselective synthesis of 1,3-dienes is an important issue in organic chemistry. In this study, we developed a reductive cross-coupling reaction between (E)-β-bromostyrenes and terminal alkynes using Cp2ZrF2, Pd(OAc)2, and a hydrosilane, which affords (E, E)-1,3-dienes in good yields. This reaction has a wide substrate scope.
Authors
- Kento Ishida (ORCID: https://orcid.org/0000-0002-0000-7304)
- Norio Sakai (ORCID: https://orcid.org/0000-0003-0722-4800)
- Yohei Ogiwara (ORCID: https://orcid.org/0000-0003-1438-0916)
- Kotone Ishizuka
Institutions
- Tokyo University of Science (JP)
Publication Details
- Journal
- Chemistry Letters
- Published
- 2026-06-09
- DOI
- https://doi.org/10.1093/chemle/upag114
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00