Compliance with the ABC pathway for integrated care of patients with atrial fibrillation in Brazil: a retrospective cohort study

Background Information about integrated care for patients with atrial fibrillation (AF) in low- and middle-income countries is scarceMethods We analyzed multicentre data from 699 patients with AF treated in São Paulo, Brazil. ABC compliance was defined as (1) adequate anticoagulation (‘A’ component); (2) controlled AF symptoms (‘B’ component); and (3) comorbidities treatment (‘C’ component). We built logistic regression models to identify characteristics associated with ABC complianceResults Mean age was 69.4 ± 14.4 years (45.8% women; 57.4% from private healthcare). Compliance with ABC pathway, and with the ‘A,’ ‘B’ and ‘C’ components occurred in 20.9%, 42.3%, 81.7% and 50.1% of the participants, respectively. Lack of ABC compliance was associated with female sex (adjusted odds ratio [aOR]:1.66; p = 0.015), intermediate (aOR:3.37; p < 0.001) and high (aOR:9.17; p < 0.001) bleeding risk. Patients with AF treated in public units had worse performance for the ‘A’ component (aOR:2.50; p < 0.001) and better performance for the ‘C’ component (aOR:0.49; p < 0.001) compared to those using private healthcare.Conclusions Compliance with the ABC pathway in São Paulo, Brazil was low. Lack of ABC compliance was more common in women and individuals with high bleeding risk. We found a mixed pattern of ABC compliance in public and private units.

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Journal
Expert Review of Cardiovascular Therapy
Published
2026-06-08
DOI
https://doi.org/10.1080/14779072.2026.2686161
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
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article

Compliance with the ABC pathway for integrated care of patients with atrial fibrillation in Brazil: a retrospective cohort study

Tiffany E Gooden, Flávia Ppl Lopes, Paulo A. Lotufo, Itamar S Santos et al.
Expert Review of Cardiovascular Therapy
Atrial Fibrillation Management and Outcomes
article

Compliance with the ABC pathway for integrated care of patients with atrial fibrillation in Brazil: a retrospective cohort study

Tiffany E Gooden, Flávia Ppl Lopes, Paulo A. Lotufo, Itamar S Santos, Alessandra C. Goulart, Carla Romagnolli Quintino, Ana C Varella, Rodrigo Diaz Olmos, Gregory YH Lip, I M Bensenor, G Neil Thomas, Otávio CE Gebara, Ana TA Lopes
article en

Abstract

Background Information about integrated care for patients with atrial fibrillation (AF) in low- and middle-income countries is scarceMethods We analyzed multicentre data from 699 patients with AF treated in São Paulo, Brazil. ABC compliance was defined as (1) adequate anticoagulation (‘A’ component); (2) controlled AF symptoms (‘B’ component); and (3) comorbidities treatment (‘C’ component). We built logistic regression models to identify characteristics associated with ABC complianceResults Mean age was 69.4 ± 14.4 years (45.8% women; 57.4% from private healthcare). Compliance with ABC pathway, and with the ‘A,’ ‘B’ and ‘C’ components occurred in 20.9%, 42.3%, 81.7% and 50.1% of the participants, respectively. Lack of ABC compliance was associated with female sex (adjusted odds ratio [aOR]:1.66; p = 0.015), intermediate (aOR:3.37; p < 0.001) and high (aOR:9.17; p < 0.001) bleeding risk. Patients with AF treated in public units had worse performance for the ‘A’ component (aOR:2.50; p < 0.001) and better performance for the ‘C’ component (aOR:0.49; p < 0.001) compared to those using private healthcare.Conclusions Compliance with the ABC pathway in São Paulo, Brazil was low. Lack of ABC compliance was more common in women and individuals with high bleeding risk. We found a mixed pattern of ABC compliance in public and private units.

Expert Review of Cardiovascular Therapy
Universidade Federal do Rio de Janeiro (BR), Medical University of Białystok (PL), University of Liverpool (GB), Universidade de São Paulo (BR), Liverpool Heart and Chest Hospital (GB), Hospital Santa Paula (BR), Disabled Athlete Sports Association (US), Liverpool John Moores University (GB), University of Birmingham (GB), Aalborg University (DK)
Openalex Percentile: Top 6%
Atrial Fibrillation Management and Outcomes
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