mGem: Tapping into the language of symbiosis to advance human microbiome research

In human microbiome research, the term "commensal" is often used to describe organisms that benefit their hosts. In ecology, in host-microbe symbiosis, a commensal organism has no impact on its host, whereas a mutualist organism benefits its host. While others have recognized this discrepancy in terminology use, old habits are hard to break, and the human microbiome community has continued in this vein. This is our call to action for the human microbiome community to use more precise terminology that appropriately reflects the impact that these microbes have on their hosts. We should use the terms "commensal" and "mutualist" when we know the effect on the host, and "symbiont" when we do not. By using the same terminology as ecologists, we will be able to make use of, and contribute to the vast research in the field of symbiosis.

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Publication Details

Journal
mBio
Published
2026-06-09
DOI
https://doi.org/10.1128/mbio.03661-25
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00

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article

mGem: Tapping into the language of symbiosis to advance human microbiome research

Gina R. Lewin, Lily Khadempour
mBio
Gut microbiota and health
article

mGem: Tapping into the language of symbiosis to advance human microbiome research

Gina R. Lewin, Lily Khadempour
article en

Abstract

In human microbiome research, the term "commensal" is often used to describe organisms that benefit their hosts. In ecology, in host-microbe symbiosis, a commensal organism has no impact on its host, whereas a mutualist organism benefits its host. While others have recognized this discrepancy in terminology use, old habits are hard to break, and the human microbiome community has continued in this vein. This is our call to action for the human microbiome community to use more precise terminology that appropriately reflects the impact that these microbes have on their hosts. We should use the terms "commensal" and "mutualist" when we know the effect on the host, and "symbiont" when we do not. By using the same terminology as ecologists, we will be able to make use of, and contribute to the vast research in the field of symbiosis.

mBio
Rutgers, The State University of New Jersey (US), Rutgers Sexual and Reproductive Health and Rights (NL), Center for Global Health (US), Case Western Reserve University (US)
National Science Foundation, National Institutes of Health, National Science Foundation of Sri Lanka
Openalex Percentile: Top 10%
Gut microbiota and health
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