Polysaccharide–Protein Complex from <i>Sargassum fusiforme</i> : Fractionation, Characterization, and Hypoglycemic Activity

value of 5.23 ± 0.85 μg/mL. After simulated gastrointestinal digestion, its inhibitory activity remained stable with no significant decrease. In an insulin-resistant (IR) HepG2 cell model, treatment with SFPr-PS3A effectively promoted glucose uptake and glycogen synthesis, concomitant with the upregulation of the protein expression of Akt and GLUT2.

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Publication Details

Journal
Journal of Agricultural and Food Chemistry
Published
2026-06-09
DOI
https://doi.org/10.1021/acs.jafc.6c03586
Primary Topic
Seaweed-derived Bioactive Compounds
Type
article
Field-Weighted Citation Impact
0.00

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article

Polysaccharide–Protein Complex from Sargassum fusiforme : Fractionation, Characterization, and Hypoglycemic Activity

Cuifang Wang, Le Dong, Chaoyang Chen, Sinan Chen et al.
Journal of Agricultural and Food Chemistry
Seaweed-derived Bioactive Compounds
article

Polysaccharide–Protein Complex from Sargassum fusiforme : Fractionation, Characterization, and Hypoglycemic Activity

Cuifang Wang, Le Dong, Chaoyang Chen, Sinan Chen, Chao Zhao, Mengyan Huang, Fang Wang
article en

Abstract

value of 5.23 ± 0.85 μg/mL. After simulated gastrointestinal digestion, its inhibitory activity remained stable with no significant decrease. In an insulin-resistant (IR) HepG2 cell model, treatment with SFPr-PS3A effectively promoted glucose uptake and glycogen synthesis, concomitant with the upregulation of the protein expression of Akt and GLUT2.

Journal of Agricultural and Food Chemistry
Quanzhou Normal University (CN), Fujian Agriculture and Forestry University (CN), College of Marin (US)
Natural Science Foundation of Fujian Province
Openalex Percentile: Top 6%
Seaweed-derived Bioactive Compounds
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