Enantiodivergent Construction of <i>Oxa</i> -Quaternary Carbon Centers via Desymmetrization Based on Palladium/Chiral Norbornene Cooperative Catalysis
]chromene products. In addition to the experimental studies, DFT calculations are performed to elucidate the reaction mechanism, the origin of enantiodiscrimination, and enantioselectivity inversion in this desymmetrization process.
Authors
- Jinxiang Ye (ORCID: https://orcid.org/0000-0002-5538-1301)
- Q Zhang
- Qianghui Zhou (ORCID: https://orcid.org/0000-0002-8125-0380)
- Ze‐Shui Liu (ORCID: https://orcid.org/0009-0000-6477-3529)
- Hong‐Gang Cheng (ORCID: https://orcid.org/0000-0001-9585-9093)
- Zhongliu Sun
- Yi-Xiang Wang (ORCID: https://orcid.org/0000-0002-5246-5497)
- Dandan Yang
Institutions
- Wuhan University (CN)
- Ministry of Education (IR)
- Green Chemistry (PL)
- Hubei University of Technology (CN)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2026-06-09
- DOI
- https://doi.org/10.1021/jacs.6c08309
- Primary Topic
- Axial and Atropisomeric Chirality Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China