Graph neural networks for networked analysis of gestational diabetes risk factors: a multi method framework

Gestational diabetes mellitus, often known as GDM, is a major health issue that causes complications for mothers and requires patient data prediction models that are complex and variable. The research in question makes use of graph-based learning in order to investigate the ways in which genetic, biochemical, and demographic elements interact in a variety of different contexts. Through the use of nodes to represent patients and lines to represent the things that they share in common, the framework illustrates how the aforementioned elements influence the likelihood of illness. Graph neural networks are utilized for the process, while BioBERT embeddings are utilized for the management of unstructured clinical notes. Graph neural networks are utilized for organized clinical notes. Because of this alignment, healthcare processes are placed in the context in which they should be, rather than being taken out of context while they are being carried out. The graph architecture used in BioBERT incorporates semantic patterns derived from medical information into a relational structure that illustrates the degree to which patients are similar to one another. After being evaluated on a substantial clinical dataset, the proposed method is able to make more accurate and readable predictions than the baseline models. The results of this study indicate that the utilization of graph architecture with both organized and unstructured data can assist in the discovery of novel approaches to the treatment of GDM that go beyond performance sets. According to the findings of the study, machine learning needs to be modified so that it can be used with healthcare applications.

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Publication Details

Journal
Scientific Reports
Published
2026-06-09
DOI
https://doi.org/10.1038/s41598-026-57000-8
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
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article

Graph neural networks for networked analysis of gestational diabetes risk factors: a multi method framework

Chanumolu Kiran Kumar, Poluru Eswaraiah, Shaik Abdul Nabi, Uddagiri Sirisha et al.
Scientific Reports
Gestational Diabetes Research and Management
article

Graph neural networks for networked analysis of gestational diabetes risk factors: a multi method framework

Chanumolu Kiran Kumar, Poluru Eswaraiah, Shaik Abdul Nabi, Uddagiri Sirisha, Kranthi Kumar Lella, G. Muni Nagamani
article en

Abstract

Gestational diabetes mellitus, often known as GDM, is a major health issue that causes complications for mothers and requires patient data prediction models that are complex and variable. The research in question makes use of graph-based learning in order to investigate the ways in which genetic, biochemical, and demographic elements interact in a variety of different contexts. Through the use of nodes to represent patients and lines to represent the things that they share in common, the framework illustrates how the aforementioned elements influence the likelihood of illness. Graph neural networks are utilized for the process, while BioBERT embeddings are utilized for the management of unstructured clinical notes. Graph neural networks are utilized for organized clinical notes. Because of this alignment, healthcare processes are placed in the context in which they should be, rather than being taken out of context while they are being carried out. The graph architecture used in BioBERT incorporates semantic patterns derived from medical information into a relational structure that illustrates the degree to which patients are similar to one another. After being evaluated on a substantial clinical dataset, the proposed method is able to make more accurate and readable predictions than the baseline models. The results of this study indicate that the utilization of graph architecture with both organized and unstructured data can assist in the discovery of novel approaches to the treatment of GDM that go beyond performance sets. According to the findings of the study, machine learning needs to be modified so that it can be used with healthcare applications.

Scientific Reports
Siddhartha Medical College (IN), Vignan's Foundation for Science, Technology & Research (IN), Manipal Academy of Higher Education (IN), Indian Institute of Technology Hyderabad (IN), Koneru Lakshmaiah Education Foundation (IN)
Good health and well-being
Openalex Percentile: Top 6%
Gestational Diabetes Research and Management
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