Variable efficacy of the non-covalent KRAS<sup>G12D</sup> inhibitor (MRTX-1133) with obesity in murine pancreatic cancer.

Authors

Lyse A. Norian (ORCID: https://orcid.org/0000-0003-1016-313X)
Henry Nnaemeka Ogbonna (ORCID: https://orcid.org/0000-0003-2740-1683)
Jianqing Zhang (ORCID: https://orcid.org/0000-0001-5246-3371)
Pia Muri
Dhana Sekar Reddy Bandi
Karen Aikhionbare
Cherlene Hardy
J B Foote
Sujith Sarvesh
Ganji Purnachandra Nagaraju
Bassel F El-Rayes
Holly Stephens

Institutions

University of Kentucky (US)
University of Alabama at Birmingham (US)
University of California San Diego Medical Center (US)

Publication Details

Journal: PubMed
Published: 2026-06-08
DOI: https://doi.org/10.1038/s41698-026-01493-z
Primary Topic: Peptidase Inhibition and Analysis
Type: article
Field-Weighted Citation Impact: 0.00

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article

Variable efficacy of the non-covalent KRAS^G12D inhibitor (MRTX-1133) with obesity in murine pancreatic cancer.

Lyse A. Norian, Henry Nnaemeka Ogbonna, Jianqing Zhang, Pia Muri et al.

Jun 8, 2026

PubMed

Peptidase Inhibition and Analysis

article

Variable efficacy of the non-covalent KRAS^G12D inhibitor (MRTX-1133) with obesity in murine pancreatic cancer.

Lyse A. Norian, Henry Nnaemeka Ogbonna, Jianqing Zhang, Pia Muri, Dhana Sekar Reddy Bandi, Karen Aikhionbare, Cherlene Hardy, J B Foote, Sujith Sarvesh, Ganji Purnachandra Nagaraju, Bassel F El-Rayes, Holly Stephens

June 8, 2026article en

Abstract

No abstract available for this paper.

PubMed

University of Kentucky (US), University of Alabama at Birmingham (US), University of California San Diego Medical Center (US)

Good health and well-being

Openalex Percentile: Top 7%

Peptidase Inhibition and Analysis

DOI Source OpenAlex

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