Shared-Reference Disease-State Geometry Exceeds Paired Pharmacology Effects in Parkinson ON/OFF Auditory Oddball EEG

This deposit contains the manuscript and supplementary materials for a mixed-contract NeuralManifoldDynamics analysis of OpenNeuro ds003490 Parkinson ON/OFF auditory oddball EEG. The study separates shared-reference disease-state inference from paired medication inference, showing broad disease-state geometry in Parkinson OFF and persistent non-control structure in Parkinson ON, while paired OFF-ON pharmacology effects remain narrow. Files include the main article, supplementary methods/data/robustness notes, figures, and supporting result tables.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-06-08
DOI
https://doi.org/10.5281/zenodo.20597114
Primary Topic
Functional Brain Connectivity Studies
Type
preprint
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preprint

Shared-Reference Disease-State Geometry Exceeds Paired Pharmacology Effects in Parkinson ON/OFF Auditory Oddball EEG

Robin Langell
Zenodo (CERN European Organization for Nuclear Research)
Functional Brain Connectivity Studies
preprint

Shared-Reference Disease-State Geometry Exceeds Paired Pharmacology Effects in Parkinson ON/OFF Auditory Oddball EEG

Robin Langell
preprint en

Abstract

This deposit contains the manuscript and supplementary materials for a mixed-contract NeuralManifoldDynamics analysis of OpenNeuro ds003490 Parkinson ON/OFF auditory oddball EEG. The study separates shared-reference disease-state inference from paired medication inference, showing broad disease-state geometry in Parkinson OFF and persistent non-control structure in Parkinson ON, while paired OFF-ON pharmacology effects remain narrow. Files include the main article, supplementary methods/data/robustness notes, figures, and supporting result tables.

Zenodo (CERN European Organization for Nuclear Research)
Kemakta Konsult (SE)
Functional Brain Connectivity Studies
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