Three new iridoid glycosides from the roots of <i>Nardostachys jatamansi</i>

In this study, the phytochemical profile of the roots of Nardostachys jatamansi was investigated, leading to the isolation of four iridoid glycosides, including three new compounds: 2”-acetyl-valerosidate (1), 3”-acetyl-valerosidate (2), 10-deoxy-sambucuside F-3”-acetyl (3), and one known compound: 7-deoxy-10-acetyl-loganic acid (4). Their structures were determined by UV, IR, HRESIMS, and NMR data. Screening for anti-hepatocyte injury activity was conducted, and compounds 1 and 3 exhibited significant protective activity.