Real-Time Visualization of Turbulent Micromixing in a T-Mixer: Submillisecond Homogenization Revealed by Chemiluminescence

, indicating that turbulent stretching-dominated homogenization drives such quick micromixing even in the large-diameter T-mixer used in flow chemistry. By experimentally defining mixing time through direct observation of homogenization, without invoking reaction models or assumed micromixing parameters, this work establishes a general framework for designing mixers and reaction lengths for better utilization of short-lived intermediates and high-throughput flow chemistry.

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Journal
Analytical Chemistry
Published
2026-06-08
DOI
https://doi.org/10.1021/acs.analchem.6c00988
Primary Topic
Innovative Microfluidic and Catalytic Techniques Innovation
Type
article
Field-Weighted Citation Impact
0.00

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article

Real-Time Visualization of Turbulent Micromixing in a T-Mixer: Submillisecond Homogenization Revealed by Chemiluminescence

Yuki Ishii, Shusaku Asano, Ken Onda, Aiichiro Nagaki et al.
Analytical Chemistry
Innovative Microfluidic and Catalytic Techniques Innovation
article

Real-Time Visualization of Turbulent Micromixing in a T-Mixer: Submillisecond Homogenization Revealed by Chemiluminescence

Yuki Ishii, Shusaku Asano, Ken Onda, Aiichiro Nagaki, Yosuke Ashikari, Hiromichi V. Miyagishi, Kiyoshi Miyata, Tomohiro Ogawa
article en

Abstract

, indicating that turbulent stretching-dominated homogenization drives such quick micromixing even in the large-diameter T-mixer used in flow chemistry. By experimentally defining mixing time through direct observation of homogenization, without invoking reaction models or assumed micromixing parameters, this work establishes a general framework for designing mixers and reaction lengths for better utilization of short-lived intermediates and high-throughput flow chemistry.

Analytical Chemistry
Kyushu University (JP), Hokkaido University (JP)
Takahashi Industrial and Economic Research Foundation, Japan Agency for Medical Research and Development, Kyushu University, Japan Society for the Promotion of Science, ACT-X
Openalex Percentile: Top 11%
Innovative Microfluidic and Catalytic Techniques Innovation
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