Evoked Neural Geometry Under Photic Stress in Alzheimer Disease and Frontotemporal Dementia

This pre-print examines evoked neural geometry during photic stress in Alzheimer disease and frontotemporal dementia using EEG, NeuralManifoldDynamics, and a resting-state reference. The analysis identifies a narrow AD-versus-healthy group effect on global Jacobian stress metrics and broader diagnosis-specific MMSE-linked structure, especially frontal associations in FTD, supporting photic stress testing as a bounded probe of dementia-related neural dynamics.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-06-08
DOI
https://doi.org/10.5281/zenodo.20593874
Primary Topic
Functional Brain Connectivity Studies
Type
preprint
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preprint

Evoked Neural Geometry Under Photic Stress in Alzheimer Disease and Frontotemporal Dementia

Robin Langell
Zenodo (CERN European Organization for Nuclear Research)
Functional Brain Connectivity Studies
preprint

Evoked Neural Geometry Under Photic Stress in Alzheimer Disease and Frontotemporal Dementia

Robin Langell
preprint en

Abstract

This pre-print examines evoked neural geometry during photic stress in Alzheimer disease and frontotemporal dementia using EEG, NeuralManifoldDynamics, and a resting-state reference. The analysis identifies a narrow AD-versus-healthy group effect on global Jacobian stress metrics and broader diagnosis-specific MMSE-linked structure, especially frontal associations in FTD, supporting photic stress testing as a bounded probe of dementia-related neural dynamics.

Zenodo (CERN European Organization for Nuclear Research)
Kemakta Konsult (SE)
Functional Brain Connectivity Studies
DOIOpen Access PDFOpenAlex
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Evoked Neural Geometry Under Photic Stress in Alzheimer Disease and Frontotemporal Dementia — Robin Langell · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS