Second Guidelines for the Diagnosis and Treatment of Vitiligo in Japan (2025)
Vitiligo is a common acquired hypopigmented disorder characterized by melanocyte damage and/or loss, primarily resulting from excessive oxidative stress and dysregulated immune responses targeting melanocytes. The initial guidelines for the diagnosis and treatment of vitiligo in Japan were published in Japanese in 2012 and in English in 2013 to provide clinical evidence for vitiligo management. Since then, there has been a substantial accumulation of pathological research and therapeutic evidence. The second guidelines for the diagnosis and treatment of vitiligo in Japan (2025) are presented as an updated resource for clinicians, incorporating worldwide expert recommendations and recent advances in basic and clinical research. These guidelines aim to provide updated knowledge for individuals with vitiligo, public health professionals, scientists, and dermatologists.
Authors
- Kazuhiro Toriyama (ORCID: https://orcid.org/0000-0002-5103-189X)
- Kenshi Yamasaki (ORCID: https://orcid.org/0000-0002-5495-4956)
- Yuta Araki (ORCID: https://orcid.org/0000-0003-3916-1525)
- SHINTARO INOUE
- Tamihiro Kawakami (ORCID: https://orcid.org/0000-0001-6741-939X)
- Atsushi Tanemura (ORCID: https://orcid.org/0000-0002-5239-8474)
- Sho Hiroyasu (ORCID: https://orcid.org/0000-0002-8290-2272)
- Yutaka Shimomura (ORCID: https://orcid.org/0000-0001-9727-8073)
- Shigetoshi Sano (ORCID: https://orcid.org/0000-0002-9812-0216)
- Kayoko Matsunaga (ORCID: https://orcid.org/0000-0001-5096-3006)
- Hiroyuki Murota (ORCID: https://orcid.org/0000-0002-0450-1377)
- Akimichi Morita (ORCID: https://orcid.org/0000-0001-8372-3754)
- Ken Okamura (ORCID: https://orcid.org/0000-0001-7366-3233)
- Tamio Suzuki
- Naoki Oiso (ORCID: https://orcid.org/0000-0001-5593-6496)
- Ichiro Katayama
- Daisuke Tsuruta
- Lingli Yang
Institutions
- Yamagata University (JP)
- University of Nagasaki (JP)
- Fujita Health University (JP)
- Gifu Pharmaceutical University (JP)
- Yamaguchi University (JP)
- Osaka City University (JP)
- Nagoya City University (JP)
- Nara City Hospital (JP)
- Tohoku Medical and Pharmaceutical University Hospital (JP)
- Toshima Hospital (JP)
- Nagasaki University (JP)
- Osaka Metropolitan University (JP)
- Tokyo Metropolitan University (JP)
- Kōchi University (JP)
- Tohoku Medical and Pharmaceutical University (JP)
- Kindai University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- The Journal of Dermatology
- Published
- 2026-05-31
- DOI
- https://doi.org/10.1111/1346-8138.70313
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 0.00