Combining bioinformatics and machine learning to analyze and validate sepsis-related cell senescence genes and potential drugs

models of sepsis-induced acute kidney injury (AKI), fenofibrate has been observed to alleviate senescence and inflammation. In conclusion, the present study identified eight DE-SRGs associated with sepsis and validated their diagnostic efficacy. And, fenofibrate might exert anti-inflammatory and anti-senescence effects in sepsis-induced AKI by regulating senescence genes, shedding fresh light on sepsis treatment.