Glycation Corrosion Index (GCI) for Modeling Cumulative Glycemic Exposure and Multi-Organ Diabetic Complication Risk: A Mathematical Framework with Lo-Shu Spatial Visualization and NHANES-Based Exploratory Analysis

v2 (peer-review revised). Key changes: (1) Title revised to 'exploratory analysis'; (2) Lo-Shu repositioned as visualization scaffold only, not causal claim; (3) k_i derivation table with DCCT/EDIC + UKPDS sources added; (4) Full logistic regression: HbA1c OR=1.09 p=0.557 (ns), Age OR=1.74 p=0.0005 (***), Sex(M) OR=1.92 p<0.0001; (5) Bootstrap 95% CI for all HbA1c strata; (6) Cochran-Armitage trend test Z=0.91 p=0.363; (7) Null result reframed: cross-sectional HbA1c failure motivates IGCI. Core framework: GCI=max(HbA1c-5.7,0), IGCI=integral(GCI)dt, dD_i/dt = k_i*GCI - r_i*D_i for nine organ systems.