Integration of Plant Leaf Vascular Scaffolds and Organ Organoids: A Structural Hypothesis for Heart, Liver, Brain, and Kidney Applications

This paper presents the hypothesis that integrating decellularized plant leaf vascular scaffolds with organ organoids can structurally resolve the vascularization problem common to heart, liver, brain, and kidney organoid research. No prior literature combining plant leaf scaffolds with multiple organ organoids as a unified approach has been identified. This paper calls upon researchers in each field to initiate data exchange and integrated experiments.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-05-31
DOI
https://doi.org/10.5281/zenodo.20470304
Primary Topic
Tissue Engineering and Regenerative Medicine
Type
preprint
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preprint

Integration of Plant Leaf Vascular Scaffolds and Organ Organoids: A Structural Hypothesis for Heart, Liver, Brain, and Kidney Applications

Akihiro Watanabe
Zenodo (CERN European Organization for Nuclear Research)
Tissue Engineering and Regenerative Medicine
preprint

Integration of Plant Leaf Vascular Scaffolds and Organ Organoids: A Structural Hypothesis for Heart, Liver, Brain, and Kidney Applications

Akihiro Watanabe
preprint en

Abstract

This paper presents the hypothesis that integrating decellularized plant leaf vascular scaffolds with organ organoids can structurally resolve the vascularization problem common to heart, liver, brain, and kidney organoid research. No prior literature combining plant leaf scaffolds with multiple organ organoids as a unified approach has been identified. This paper calls upon researchers in each field to initiate data exchange and integrated experiments.

Zenodo (CERN European Organization for Nuclear Research)
Tissue Engineering and Regenerative Medicine
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Integration of Plant Leaf Vascular Scaffolds and Organ Organoids: A Structural Hypothesis for Heart, Liver, Brain, and Kidney Applications — Akihiro Watanabe · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS