Peripartum Cardiomyopathy Presenting With Severe Biventricular Dysfunction, Valvular Regurgitation, and Familial Predisposition: A Case Report

ABSTRACT Peripartum cardiomyopathy (PPCM) is defined as the onset of left ventricular systolic dysfunction either during pregnancy or up to 5 months after delivery, without any other known cause of heart failure. The exact pathogenesis of this disease is unknown, and its prognosis remains poorly understood. We present a case of a 27‐year‐old woman presenting at 37 + 3 weeks of gestation, with reduced ejection fraction, biventricular systolic dysfunction and dilation, and valvular regurgitation. She was managed with medications slightly different from guideline‐mediated standard therapy. The unique and most crucial detail of this case is that it showed a close family history of PPCM, as the patient's older sister had also died of the same cause. Learning objectives: genetic and familial risk of developing peripartum cardiomyopathy.