Galleri MCED Test Fails to Meet Primary Endpoint in Large Trial

Data unveiled at this year's ASCO Annual meeting show that GRAIL's Galleri multi-cancer early detection (MCED) test failed to reduce stage III and IV cancers in the landmark NHS-Galleri trial, although there was an improvement in stage IV alone. Experts say the findings fall short of demonstrating a large enough clinical benefit for MCED testing that would warrant Galleri's implementation.

Publication Details

Journal
Cancer Discovery
Published
2026-05-30
DOI
https://doi.org/10.1158/2159-8290.cd-nw2026-0060
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Galleri MCED Test Fails to Meet Primary Endpoint in Large Trial

Cancer Discovery
Prostate Cancer Diagnosis and Treatment
article

Galleri MCED Test Fails to Meet Primary Endpoint in Large Trial

article en

Abstract

Data unveiled at this year's ASCO Annual meeting show that GRAIL's Galleri multi-cancer early detection (MCED) test failed to reduce stage III and IV cancers in the landmark NHS-Galleri trial, although there was an improvement in stage IV alone. Experts say the findings fall short of demonstrating a large enough clinical benefit for MCED testing that would warrant Galleri's implementation.

Cancer Discovery
Openalex Percentile: Top 6%
Prostate Cancer Diagnosis and Treatment
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Galleri MCED Test Fails to Meet Primary Endpoint in Large Trial · Cancer Discovery (2026) | TGRS Research Map | TGRS