Breast Metastasis From Uterine Leiomyosarcoma: A Case Report

Breast metastases from extramammary malignancies are uncommon. Among these, metastatic spread from uterine leiomyosarcoma is exceptionally rare. Uterine leiomyosarcoma is an aggressive mesenchymal neoplasm characterized by early hematogenous dissemination, most commonly to the lungs, liver, peritoneum, and bone. Breast involvement is distinctly unusual and may mimic primary breast carcinoma both clinically and radiologically. We report the case of a 76-year-old woman who presented with a painless enlarging mass in the upper outer quadrant of the left breast three months after hysterectomy with bilateral salpingo-oophorectomy for high-grade uterine leiomyosarcoma. Fine-needle aspiration suggested metastatic mesenchymal neoplasm, and wide local excision confirmed metastatic leiomyosarcoma. This case highlights the importance of considering metastatic disease in patients with a history of uterine sarcoma who develop new breast lesions.